The Interplay between the Escherichia coli Rho Guanine Nucleotide Exchange Factor Effectors and the Mammalian RhoGEF Inhibitor EspH
ABSTRACT Rho GTPases are important regulators of many cellular processes.Subversion of Rho GTPases is a common infection strategy employed by many important Bath Chairs human pathogens.Enteropathogenic Escherichia coli and enterohemorrhagic Escherichia coli (EPEC and EHEC) translocate the effector EspH, which inactivates mammalian Rho guanine excha